Nucleophilic conjugate trifluoromethylation of chromones and activated alkenes under the action of Ruppert’s reagent

V. Ya. Sosnovskikh; G.-V. Roshentaler

doi:10.15826/chimtech.2017.4.1.022

Nucleophilic conjugate trifluoromethylation of chromones and activated alkenes under the action of Ruppert’s reagent

V. Ya. Sosnovskikh, G.-V. Roshentaler

Abstract

This review summarizes data on the reactions of chromones and activated alkenes with trimethyl(trifluoromethyl)silane (Ruppert’s reagent), which occures as a nucleophilic 1,4-trifluoromethylation with high regioselectivity and good yields. The most important chemical properties of the formed products are also considered.

Keywords

chromones; activated alkenes; nucleophilic 1,4-trifluoromethylation; trimethyl(trifluoromethyl)silane

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DOI: https://doi.org/10.15826/chimtech.2017.4.1.022

Copyright (c) 2017 V. Ya. Sosnovskikh, G.-V. Roshentaler

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