New molecular complex of ammonium glycyrrhizate with rutin

L. A. Yakovishin; V. D. Ratnikov; P. I. Bazhan; G. P. Zaitsev

doi:10.15826/chimtech.2022.9.1.01

New molecular complex of ammonium glycyrrhizate with rutin

L. A. Yakovishin, V. D. Ratnikov, P. I. Bazhan, G. P. Zaitsev

Abstract

A new 1:1 molecular complex of triterpene glycoside ammonium glycyrrhizate (GC) with flavonoid glycoside rutin (Rut) was obtained in aqueous ethanol. The stability constant (9.7±0.2)×10⁴ (mol/L)^–1 was calculated for the complex via isomolar curves. The complexation was studied by UV- and ATR IR-Fourier spectroscopy and a method of isomolar series. The hydrogen bonds and hydrophobic interactions are formed in the molecular complex. A preliminary antioxidant activity assessment of the complex was made.

Keywords

triterpene glycosides; ammonium glycyrrhizate; rutin; molecular complex; antioxidant capacity

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References

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DOI: https://doi.org/10.15826/chimtech.2022.9.1.01

Copyright (c) 2021 L.A. Yakovishin, V.D. Ratnikov, P.I. Bazhan, G.P. Zaitsev

This work is licensed under a Creative Commons Attribution 4.0 International License.

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