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Mechanosynthesis of equol-based polycarbonate and polyester as chemosensors for detection of nitro-explosives

Wahab K.A. Al-Ithawi, Artem V. Baklykov, Vadim A. Platonov, Youcef Ballou, Omkar Pokharkar, Albert F. Khasanov, Igor S. Kovalev, Igor L. Nikonov, Dmitry S. Kopchuk, Rina F. Samigullina, Yurii M. Shafran, Nikolay A. Belyaev, Grigory V. Zyryanov

Abstract


Equol (4',7-isoflavandiol) is a metabolite of isoflavandiol estrogen daidzein, which is found in soybeans and other plant sources. In this manuscript we wish to report the first mechanochemical approach to equol-based polymers, such as polycarbonate and polyester. Our approach involves the polycondensation reaction between 4',7-isoflavandiol (rac-equol) and triphosgene or oxalyl chloride under ball-milling conditions. The obtained polymers were characterized by means of 1H NMR- and IR-spectroscopy. To explore the possibility of practical application of the abovementioned polymers, the fluorescence “turn-off” response of the equol-based polycarbonate towards some common nitroanalytes (2,4-dinitrotioluene (DNT) and 2,4,6-trinitrophenol (picric acid, PA)) was investigated, and up to 1o5 M–1 Stern-Volmer constants were observed.

Keywords


equol; mechanosynthesis; polymers; fluorescence quenching; nitro-explosives visual detection

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DOI: https://doi.org/10.15826/chimtech.2025.12.3.06

Copyright (c) 2025 Wahab K.A. Al-Ithawi, Artem V. Baklykov, Vadim A. Platonov, Youcef Ballou, Omkar Pokharkar, Albert F. Khasanov, Igor S. Kovalev, Igor L. Nikonov, Dmitry S. Kopchuk, Rina F. Samigullina, Yurii M. Shafran, Nikolay A. Belyaev, Grigory V. Zyryanov

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